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potato extract
- Development stage
- Preclinical
- Lead developer
- Kerry
- Modality
- Small Molecules
- Administration
- Oral, Topical
01
Overview
Potato extract is a preparation made from the tuber of *Solanum tuberosum* and includes a variety of fractions, most notably standardized forms such as Slendesta, which contains 5% proteinase inhibitor II (PPI II)[1]. Its most researched mechanism is appetite suppression via stimulation of cholecystokinin (CCK) release, leading to delayed gastric emptying and enhanced satiety in humans and experimental animals. Preclinical studies suggest anti-obesity and anti-diabetic effects in mouse models associated with weight and fat reduction, normalization of food consumption, and improvements in metabolic parameters[1]. Broader potato extracts and potato peel extracts also display anti-inflammatory, antioxidant, and antimicrobial properties, as well as uses in food, cosmetic, and industrial applications[2][4][5].
- Brand names
- Slendesta
- Other names
- potato proteinase inhibitor II concentratePPI II concentrateSolanum tuberosum extractpotato peel extractpotato liquid extract
02
Targets
PRSS3 (Trypsin-3)
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