Drug intelligence / Profile preview

PoultrySulfa

Development stage
Unknown
Lead developer
Huvepharma
Modality
Small Molecules
Administration
Oral
01

Overview

PoultrySulfa is an FDA-approved veterinary antibiotic combination consisting of three sulfonamides: sulfamerazine, sulfamethazine, and sulfaquinoxaline. Developed by Huvepharma (and previously marketed by Alpharma), it is formulated as a water-soluble powder for administration via drinking water to chickens and turkeys. It is indicated for the control of coccidiosis caused by *Eimeria* species (such as *E. meleagrimitis* and *E. adenoeides*) and acute fowl cholera caused by *Pasteurella multocida*. As a sulfonamide combination, it works by inhibiting bacterial and protozoal dihydropteroate synthase, thereby blocking the synthesis of dihydrofolic acid and interfering with nucleic acid production. It is the only triple-sulfa veterinary product approved by the FDA in the United States.

Brand names
PoultrySulfa
Other names
sulfamerazine + sulfamethazine + sulfaquinoxaline
02

Targets

DHPS (Dihydropteroate synthase)

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