Drug intelligence / Profile preview

Poulvac Procerta HVT-IBD

Development stage
Unknown
Lead developer
Zoetis
Modality
Viral Vector Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Subcutaneous, In Ovo
01

Overview

Poulvac Procerta HVT-IBD is a veterinary vaccine for poultry that uses a recombinant serotype 3 turkey herpesvirus (HVT) as a vector to express the VP2 protein of infectious bursal disease virus (IBDV). This live, cell-associated vaccine is designed for active immunization of chickens and embryonated chicken eggs to reduce mortality, clinical signs, and lesions caused by Marek’s disease virus and to prevent mortality and clinical signs while reducing lesions caused by infectious bursal disease virus. The mechanism involves the expression of IBDV VP2 antigen via the non-pathogenic turkey herpesvirus vector in vaccinated birds, stimulating protective immunity against both diseases. The product is administered either subcutaneously to day-old chicks or in ovo to 18–19-day-old embryonated eggs. Developed specifically for poultry health management programs, it provides early onset protection with at least 63 days’ duration against IBDV[2][3][6][8].

Brand names
Poulvac Procerta HVT-IBD
Other names
Bursal Disease-Marek’s Disease Vaccine, Serotype 3, Live Marek’s Disease Vector
02

Targets

Host adaptive immune receptors recognizing Infectious Bursal Disease Virus VP2VP2 (Infectious bursal disease virus VP2 protein)

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