Drug intelligence / Profile preview

povidone-iodine + bupivacaine hydrochloride + triamcinolone acetonide + lidocaine

Development stage
Unknown
Lead developer
Asclemed USA
Modality
Small Molecules
Administration
Intraarticular, Parenteral, Topical, Percutaneous
01

Overview

povidone-iodine + bupivacaine hydrochloride + triamcinolone acetonide + lidocaine is a multi-component small-molecule procedural kit that combines two amide local anesthetics, one corticosteroid, and one antiseptic for office-based or procedural pain-management use. Bupivacaine and lidocaine produce local or regional anesthesia by reversibly blocking voltage-gated sodium channels in peripheral nerves, triamcinolone acetonide provides anti-inflammatory activity through glucocorticoid receptor agonism, and povidone-iodine serves as a topical antiseptic by releasing iodine that disrupts microbial proteins and membranes. Publicly described examples include DailyMed-listed kits such as BLT-25 KIT and MLK F4 KIT; these kit listings indicate they have not been found by FDA to be safe and effective, consistent with assembled or compounding-style procedural products rather than an FDA-approved branded therapeutic asset. The product is primarily associated with local or regional anesthesia, analgesia, and adjunctive inflammation control around injections, joint procedures, or nerve blocks.

Brand names
BLT-25 KITBLT25 KITBLT 25 KITMLK F4 KIT
Other names
povidone-iodine + bupivacaine hydrochloride + triamcinolone acetonide + lidocainepovidone-iodine + bupivacaine hydrochloride + triamcinolone acetonide + lidocaine hydrochloride
02

Targets

GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)

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