Drug intelligence / Profile preview

povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + methylprednisolone acetate

Development stage
Unknown
Lead developer
Asclemed USA
Modality
Small Molecules
Administration
Intramuscular, Intraarticular, Intralesional, Topical
01

Overview

A multi-component procedural injection kit containing **povidone-iodine**, **isopropyl alcohol**, **lidocaine hydrochloride**, and **methylprednisolone acetate**. The clinically dominant therapeutic component is methylprednisolone acetate, a depot synthetic glucocorticoid corticosteroid that binds the glucocorticoid receptor to suppress inflammatory gene expression, reduce leukocyte trafficking, and exert anti-inflammatory and immunosuppressive effects after intramuscular, intra-articular, soft tissue, or intralesional administration. The povidone-iodine swabs and isopropyl alcohol pads serve antiseptic skin-preparation roles, while lidocaine hydrochloride provides local anesthetic support for the injection procedure. Public context links this combination kit to Asclemed USA as the marketer of the DYURAL 40 KIT configuration and to Pfizer as manufacturer of the Depo-Medrol methylprednisolone acetate component. The kit itself appears to function as a convenience combination/procedural package rather than a distinct FDA-approved finished combination drug product.

Brand names
DYURAL 40 KITDYURAL40 KITDYURAL-40 KIT
Other names
povidone-iodine + isopropyl alcohol + lidocaine hydrochloride + methylprednisolone acetatemethylprednisolone acetate procedural kit
02

Targets

MR (Mineralocorticoid receptor)GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)

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