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povidone-iodine + lidocaine hydrochloride + isopropyl alcohol + bupivacaine hydrochloride
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Topical, Infiltration, Epidural, Intramuscular, Intraarticular, Intralesional, Percutaneous, Parenteral
01
Overview
This drug is a **multi-ingredient local anesthetic and antiseptic combination** containing povidone-iodine, lidocaine hydrochloride, isopropyl alcohol, and bupivacaine hydrochloride. Based on public labeling, this exact ingredient combination appears as part of an unapproved kit product listed in FDA label repositories, used for procedural anesthesia/analgesia and skin antisepsis around injection or interventional settings. Pharmacologically, lidocaine and bupivacaine are amide local anesthetics that reduce nerve conduction by blocking voltage-gated sodium channels, while povidone-iodine and isopropyl alcohol provide broad topical antimicrobial skin preparation activity. The product is best understood as a procedure-support combination product for anesthesia-related use rather than as a novel molecular entity. ([nctr-crs.fda.gov](https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/552725))
- Other names
- povidone-iodine + lidocaine hydrochloride + isopropyl alcohol + bupivacaine hydrochloride
02
Targets
NaV (Voltage-gated sodium channels)
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