Drug intelligence / Profile preview

povidone-iodine + triamcinolone acetonide + lidocaine hydrochloride + bupivacaine hydrochloride

Development stage
Unknown
Lead developer
Asclemed USA
Modality
Small Molecules
Administration
Topical, Intraarticular, Parenteral, Percutaneous
01

Overview

This product is a **multi-component procedural injection kit** containing povidone-iodine, triamcinolone acetonide, lidocaine hydrochloride, and bupivacaine hydrochloride, typically packaged for office-based pain and anesthetic procedures such as joint injections, trigger point injections, and nerve blocks. Its pharmacology combines **skin antisepsis** from povidone-iodine, **anti-inflammatory glucocorticoid activity** from triamcinolone acetonide via glucocorticoid receptor signaling, and **local anesthetic/analgesic effects** from lidocaine and bupivacaine through blockade of voltage-gated sodium channels in peripheral nerves, thereby reducing nerve impulse conduction. Publicly described versions appear as compounded or specialty-distributed kits rather than a single branded innovator drug, and the available context indicates that these kits have appeared on DailyMed with labeling stating that they have **not been found by the FDA to be safe and effective** and that the labeling has **not been approved by the FDA**.

Brand names
MLK F4 KITBLT-25 KITBLT25 KITBLT 25 KITP-CARE K40MXP-CARE K80MX
Other names
povidone-iodine + triamcinolone acetonide + lidocaine hydrochloride + bupivacaine hydrochloride
02

Targets

GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)

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