Drug intelligence / Profile preview

PR591

Development stage
Preclinical
Lead developer
Eli Lilly
Modality
Recombinant Proteins and Enzymes
01

Overview

PR591 is a preclinical asset developed by Protomer Technologies, which was acquired by Eli Lilly. It is an engineered insulin analog designed as a small protein therapeutic. This drug is glucose-responsive, meaning it is engineered to automatically activate in high-glucose conditions. Its primary aim is to reduce the risk of hypoglycemia for patients with both type 1 and type 2 diabetes by providing a more controlled insulin response.

02

Targets

INSR (Insulin receptor)

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