Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
pranoprofen + sodium hyaluronate
- Development stage
- Unknown
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Ophthalmic
01
Overview
Pranoprofen + sodium hyaluronate is a fixed-dose combination of two ophthalmic agents used primarily for the treatment of dry eye disease. Pranoprofen is a non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes, thereby reducing ocular inflammation. Sodium hyaluronate is a viscoelastic polymer that acts as an artificial tear substitute, providing lubrication and moisture to the ocular surface. The combination leverages both anti-inflammatory effects (from pranoprofen) and tear film stabilization/lubrication (from sodium hyaluronate), resulting in improved clinical outcomes for patients with dry eye compared to either agent alone. Clinical studies have shown this combination improves tear film stability, increases tear secretion, reduces corneal staining, lowers inflammatory cytokine levels (such as TNF-α and IL-1β), enhances visual function, and improves quality of life in patients with dry eye[1][2][6][8].
- Other names
- pranoprofen and sodium hyaluronatesodium hyaluronate and pranoprofen
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
Beyond the preview
Go deeper on pranoprofen + sodium hyaluronate.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on pranoprofen + sodium hyaluronate.