Drug intelligence / Profile preview

Prasaprohyai

Development stage
Phase 1
Lead developer
Thammasat University
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Prasaprohyai is a traditional Thai polyherbal formula primarily composed of *Kaempferia galanga* (sand ginger) along with nine other botanical ingredients. It is traditionally utilized in Thai medicine for the treatment of respiratory ailments and fever. Modern clinical development, led by Thammasat University, has focused on a 95% ethanolic extract of the formula for the treatment of allergic rhinitis. The extract contains bioactive compounds like ethyl-p-methoxycinnamate, which demonstrate potent anti-inflammatory and anti-allergic properties by inhibiting mast cell degranulation and reducing the production of pro-inflammatory cytokines. A Phase I clinical trial has been conducted to evaluate the safety and tolerability of 100 mg and 200 mg doses in healthy volunteers.

Brand names
prasaprohyai
Other names
Prasa Proh YaiPrasa-proh-yaiPrasaproyai
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALOX5 (Arachidonate 5-lipoxygenase)PGHS-1 (Prostaglandin G/H Synthase 1)

Beyond the preview

Go deeper on Prasaprohyai.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Prasaprohyai.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call