PreCold

PreCold is a fixed-dose combination pharmaceutical product marketed primarily in India for the symptomatic relief of the common cold and associated upper respiratory conditions. The medication integrates three active ingredients: paracetamol, phenylpropanolamine, and cetirizine. Paracetamol serves as an analgesic and antipyretic by inhibiting prostaglandin synthesis, primarily within the central nervous system, to reduce pain and fever. Phenylpropanolamine is a sympathomimetic amine that acts as a nasal decongestant by stimulating alpha-adrenergic receptors, leading to vasoconstriction of the nasal mucosa and reduction of swelling. Cetirizine is a second-generation antihistamine that provides relief from allergic symptoms such as sneezing, runny nose, and watery eyes by selectively antagonizing peripheral H1 receptors. Together, these components address the multi-symptom nature of viral respiratory infections and allergic rhinitis.

Brand names

PreCold