Drug intelligence / Profile preview

prednisolone caproate

Development stage
Preclinical
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Topical, Rectal
01

Overview

Prednisolone caproate is a synthetic corticosteroid ester, specifically the caproic acid (hexanoic acid) ester of prednisolone. It is classified as a glucocorticoid and is indicated for the treatment of hemorrhoids, anal fissures, and proctitis. Like other glucocorticoids, it exerts anti-inflammatory and immunosuppressive effects by mimicking endogenous cortisol activity. The drug acts primarily by binding to the glucocorticoid receptor, leading to altered gene expression that suppresses inflammatory mediators and immune responses[2]. Prednisolone derivatives are widely used in medicine for their ability to reduce inflammation in various tissues.

Other names
prednisolone caproateprednisolone hexanoateprednisolone-21 hexanoateprednisolone21 hexanoateprednisolone 21 hexanoate
02

Targets

GR (Glucocorticoid receptor)

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