Drug intelligence / Profile preview

prednisolone sodium metasulfobenzoate

Development stage
Approved
Lead developer
Alizyme
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral, Rectal
01

Overview

Prednisolone sodium metasulfobenzoate is a synthetic glucocorticoid corticosteroid, used primarily as an anti-inflammatory and immunosuppressive agent. It is a salt form of prednisolone designed for improved delivery, including colon-targeted formulations (e.g. ATL-2502/Colal-Pred). Like other corticosteroids, it acts by binding to the **glucocorticoid receptor**, inhibiting pro-inflammatory signals and promoting anti-inflammatory effects. It is indicated for various inflammatory and autoimmune conditions such as asthma, ulcerative colitis, and other diseases where immune suppression or inflammation reduction is required[3][5][1]. The drug may be formulated in oral solid dosage forms such as tablets or granules[5].

Brand names
COLAL-PREDPredenemaPredocolCortico-Sol
Other names
prednisolone sodium metasulfobenzoateprednisolone metasulphobenzoateprednisolone metasulfobenzoate sodium
02

Targets

GR (Glucocorticoid receptor)MR (Mineralocorticoid receptor)

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