Drug intelligence / Profile preview

prednisone + salbutamol

Development stage
Unknown
Lead developer
Bayer
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral, Inhalation
01

Overview

Prednisone + salbutamol is a combination therapy involving two distinct drugs commonly used in the management of acute asthma and other obstructive airway diseases. Prednisone is a synthetic corticosteroid that acts as an anti-inflammatory and immunosuppressant, reducing airway inflammation and mucus production. Salbutamol (also known as albuterol) is a short-acting, selective beta2-adrenergic receptor agonist that relaxes bronchial smooth muscle, leading to rapid bronchodilation and relief of bronchospasm. This combination is typically used in hospital or emergency settings for acute asthma exacerbations, where prednisone addresses underlying inflammation while salbutamol provides immediate symptomatic relief by opening airways[1][9][10]. The two drugs are usually administered separately but may be given together as part of an acute treatment protocol.

Other names
albuterol + systemic steroidsalbuterol and prednisonesalbutamol + prednisone
02

Targets

GR (Glucocorticoid receptor)ADRB2 (β2)

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