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Premi-TAT

Development stage: Unknown
Lead developer: Premium Serums and Vaccines
Modality: Antibody-Based Therapeutics
Administration: Intramuscular, Subcutaneous

Overview

Premi-TAT is an equine-derived polyclonal antitoxin developed by Premium Serums and Vaccines for the treatment and prophylaxis of tetanus. It consists of enzyme-refined equine antibodies (immunoglobulins) that specifically target and neutralize tetanospasmin, the neurotoxin produced by *Clostridium tetani*. By binding to the circulating toxin, Premi-TAT prevents it from attaching to nerve endings and causing the characteristic muscle spasms associated with the disease. The product is available in both liquid and lyophilized (freeze-dried) formulations, typically at a strength of 1500 International Units (IU), and is manufactured according to British Pharmacopoeia (B.P.) standards.

Brand names: Premi-TATPremi-TAT 1500Premi-TAT1500Premi-TAT-1500
Other names: Tetanus Antitoxin 1500 IUEquine Tetanus AntitoxinTetanus Antitoxin (Equine)Tetanus Antitoxin 1500 IU (liquid & lyophilized)

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