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**Presponse** is a commercial bovine vaccine developed by Boehringer Ingelheim Animal Health for preventing respiratory diseases in cattle. **Presponse SQ** targets pneumonic pasteurellosis by stimulating immunity against **Mannheimia haemolytica** (formerly Pasteurella haemolytica) via bacterial surface antigens and leukotoxoids. **Presponse HM** provides protection against pneumonic pasteurellosis due to **Pasteurella multocida** and respiratory disease from **Mannheimia haemolytica** in cattle 7 months or older. It is often combined in products like **Pyramid/Presponse** for broader coverage including BVD, IBR, BRSV, and PI3.[1][2][3][6][7]
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