prestin gene therapy

Prestin gene therapy is a **preclinical inner-ear gene therapy concept** intended to restore cochlear outer hair cell function by delivering a functional copy of **SLC26A5**, the gene encoding prestin, a voltage-sensitive motor protein that drives outer hair cell electromotility and cochlear amplification. The therapeutic rationale is that replacement of defective or absent prestin should re-establish outer hair cell mechanical amplification and thereby improve hearing in **SLC26A5-related hereditary hearing loss**. Published research supports this concept in animal models, but there is no clearly established, uniquely named clinical drug product, brand, or code designation identifiable from the queried term alone.

Other names

prestin gene therapySLC26A5 gene therapySLC-26A5 gene therapySLC 26A5 gene therapy