Drug intelligence / Profile preview

PresVu

Development stage
Unknown
Lead developer
Entod Pharmaceuticals
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

PresVu is a proprietary ophthalmic solution of pilocarpine hydrochloride (1.25%) developed by Entod Pharmaceuticals for the treatment of presbyopia in adults. It utilizes Dynamic Buffer Technology to adapt to the physiological pH of the tear film, enhancing comfort and ensuring consistent efficacy. Pilocarpine acts as a cholinergic muscarinic receptor agonist, stimulating the muscarinic receptors on the iris sphincter muscle to cause pupil constriction (miosis) and on the ciliary muscle to facilitate accommodation, thereby temporarily improving near and intermediate vision. Although its manufacturing and marketing license in India was temporarily suspended by the CDSCO in September 2024 due to unauthorized promotional claims, the suspension was revoked in April 2025, allowing for its commercial launch.

Brand names
PresVu
Other names
pilocarpine hydrochloride 1.25% ophthalmic solution
02

Targets

CHRM3 (M3)

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