PRF-108

PRF-108 is a proprietary formulation of the local anesthetic ropivacaine, developed to provide prolonged analgesic effects when applied locally to surgical wounds. In preclinical studies, specifically in an incisional pig model, PRF-108 demonstrated significantly longer and more effective pain relief compared to standard commercial ropivacaine solution. The extended duration of action is attributed to slower clearance from the injection site, resulting in sustained local concentrations and improved postoperative pain management. The drug has been evaluated in clinical trials for its safety and effectiveness as a long-lasting local anesthetic for postoperative pain control[1][2].