Drug intelligence / Profile preview

PRG Pro-Care Gel α

Development stage
Phase 1
Lead developer
SHOFU Dental
Modality
Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems, Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

PRG Pro-Care Gel α is a bioactive dental gel developed by SHOFU, utilizing proprietary S-PRG (Surface Pre-Reacted Glass-ionomer filler) particles. This innovative Giomer technology enables the continuous release of six types of ions: fluoride, strontium, borate, aluminum, sodium, and silicate. These ions work synergistically to reduce dental plaque adhesion, neutralize acids, protect tooth enamel, and promote remineralization. The gel is indicated for dental prophylaxis, particularly during periods of tooth eruption, orthodontic treatment, or gum recession, and for patients at high risk of dental caries. It helps to suppress enamel demineralization and can alleviate dentinal hypersensitivity.

Brand names
PRG Pro-Care Gel α
Other names
PRG Pro Care Gel
02

Targets

SLC4A11 (Brain enriched myelin associated protein 1)

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