Drug intelligence / Profile preview

PRGF-Endoret

Development stage
Phase 4
Lead developer
BTI Biotechnology Institute
Modality
Cell Therapies
Administration
Intraarticular, Intradermal, Intramuscular, Ophthalmic, Topical, Intralesional, Periarticular
01

Overview

PRGF-Endoret (Plasma Rich in Growth Factors - Endoret) is a patented autologous platelet-rich plasma (PRP) technology developed by the BTI Biotechnology Institute. It is designed to concentrate platelets from a patient's own blood to create a bioactive fibrin scaffold that releases a high concentration of essential growth factors, including PDGF, TGF-β, VEGF, and EGF. A distinguishing feature of the PRGF-Endoret system is that it is leukocyte-free, which minimizes the pro-inflammatory response often associated with white blood cells in other PRP formulations. The preparation involves a specific centrifugation process and activation with calcium chloride, avoiding bovine thrombin. It is widely utilized across multiple medical fields, including oral and maxillofacial surgery, orthopedics, dermatology, and ophthalmology, to accelerate tissue regeneration, reduce inflammation, and improve healing outcomes.

Brand names
EndoretPRGF-Endoret
Other names
Plasma Rich in Growth FactorsPRGFEndoret-PRGF

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