Prime-2-CoV

Prime-2-CoV is a viral vector vaccine candidate developed by Prime Vector Technologies for the prevention of COVID-19. It utilizes the Orf virus (ORFV), a member of the Parapoxvirus genus, as a vector platform. The vaccine is engineered to express the SARS-CoV-2 spike protein to elicit protective immune responses, including the production of neutralizing antibodies and T-cell activation. The ORFV platform is noted for its ability to induce potent immune responses without being hindered by pre-existing vector immunity in humans, potentially allowing for repeated administrations or use as a booster.

Other names

orf virus-based covid-19 vaccine boosterORFV-SARS-CoV-2 spike vaccineORFV-SARS-CoV2 spike vaccineORFV-SARS-CoV 2 spike vaccineParapoxvirus-based COVID-19 vaccine