Drug intelligence / Profile preview

Prime Bond NT

Development stage
Phase 3
Lead developer
Dentsply Sirona
Modality
Small Molecules, Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

Prime Bond NT is a light-cured, universal dental adhesive designed for bonding composite and compomer restorative materials to enamel and dentin, as well as to metals and ceramics. Developed by Dentsply Sirona, it utilizes Nano-Technology (NT) by incorporating nanofillers to enhance its physical properties and ensure a uniform, thin adhesive layer. The mechanism involves the infiltration of resin monomers into the etched tooth surface, creating a hybrid layer that provides a strong micromechanical bond. It contains PENTA (dipentaerythritol pentaacrylate monophosphate) as a functional monomer to promote adhesion to the tooth structure and cetylamine hydrofluoride to provide fluoride release. It is typically used in the total-etch technique, requiring a separate phosphoric acid etching step.

Brand names
Prime Bond NTPrime&Bond NT
Other names
Prime & Bond NT
02

Targets

COL1 (Collagen type I)

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