Drug intelligence / Profile preview

Priofect

Development stage
Unknown
Lead developer
Starpharma
Modality
Nanoparticles → Drug Delivery Systems
01

Overview

Priofect is a proprietary line of polyamidoamine (PAMAM) dendrimers developed by Starpharma, specifically engineered for the high-efficiency delivery of nucleic acids, including siRNA and DNA, as well as other therapeutic agents. These dendrimers are spherical, highly branched macromolecules with a well-defined three-dimensional structure that allows for the precise attachment or encapsulation of active pharmaceutical ingredients. Priofect functions as a transfection reagent and delivery scaffold, improving the stability, solubility, and cellular internalization of its cargo. While primarily utilized as a transfection reagent in research and diagnostic settings, the Priofect technology represents a significant application of dendrimer technology in the development of targeted therapeutic interventions.

Brand names
Priofect
Other names
PAMAM dendrimer

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