Drug intelligence / Profile preview

Pristine Cream

Development stage
Unknown
Lead developer
BOHECO
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Pristine Cream (also known as PRISTINE) is a patented, proprietary Ayurvedic skin-healing cream developed and manufactured by Bombay Hemp Company (BOHECO). Formulated with full-spectrum Vijaya (Cannabis sativa) leaf extract, the cream is rich in cannabinoids that interact locally with the skin's endocannabinoid system (ECS) to modulate CB1 and CB2 receptor activity. This interaction helps reduce inflammatory skin responses, calm itching, and support skin barrier repair. Pristine Cream is indicated for the management of chronic inflammatory skin conditions, including eczema, psoriasis, dermatitis, and persistent dry skin. It has been clinically tested in collaboration with the National Institute of Ayurveda, Jaipur, demonstrating significant improvements in Eczema Area and Severity Index (EASI) scores, itching, and dryness.

Brand names
PRISTINEPRISTINE Cream
Other names
BOHECO PRISTINEBOHECO PRISTINE Skin Healing CreamPRISTINE Skin Healing CreamPristine Medical Cannabis Salve
02

Targets

CNR1 (Cannabinoid receptor 1)

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