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PRN-002-01 is an orally administered small molecule modulator of AMPA and kainate receptors currently in Phase 1 clinical development by Proniras. The drug is designed to target ionotropic glutamate receptors to treat a variety of central nervous system (CNS) disorders. By modulating excitatory neurotransmission mediated by AMPA and kainate receptors, PRN-002-01 aims to provide therapeutic benefits in conditions where glutamatergic signaling is imbalanced. It is part of a broader pipeline of glutamate receptor modulators developed by Proniras for neurological and psychiatric indications.
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