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**Proactiv** is an over-the-counter topical acne-care brand and product portfolio originally launched by Guthy-Renker. Its products are intended to treat and help prevent acne vulgaris, including mild to moderate acne. Proactiv is not a single chemically defined drug: formulations across the brand include benzoyl peroxide, salicylic acid, adapalene, sulfur, and azelaic acid in different routines and individual products. The original Proactiv Solution three-step routine uses benzoyl peroxide-containing cleanser and repairing treatment products, while other branded routines use different active ingredients. The Proactiv business was acquired by Galderma and subsequently transferred through Alchemee to Taro, which became a wholly owned subsidiary of Sun Pharma.
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