Drug intelligence / Profile preview

Probiatop

Development stage: Phase 4
Lead developer: Probi
Modality: Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration: Oral

Overview

Probiatop is a multi-strain probiotic dietary supplement formulated to promote a healthy balance of intestinal microbiota. It contains a specific blend of four lyophilized bacterial strains: *Lactobacillus acidophilus* NCFM, *Lactobacillus rhamnosus* HN001, *Lactobacillus paracasei* Lpc-37, and *Bifidobacterium lactis* Bi-07. These strains work synergistically to colonize the gastrointestinal tract, inhibit the growth of pathogenic microorganisms through competitive exclusion and the production of antimicrobial substances (such as organic acids), and modulate the host's immune system. Probiatop is primarily indicated for the management of intestinal dysbiosis and the maintenance of digestive health. It is developed and manufactured by Libbs Farmacêutica, a prominent Brazilian pharmaceutical company.

Brand names: Probiatop
Other names: Lactobacillus rhamnosus HN001 + Lactobacillus acidophilus NCFM + Lactobacillus paracasei Lcp-37 + Bifidobacterium lactis HN019

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