Drug intelligence / Profile preview

Probiotic Pur

Development stage
Unknown
Lead developer
Van Yuzuncu Yil University
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Probiotic Pur is a multi-strain probiotic dietary supplement that was evaluated in a Phase 3 clinical trial led by Yuzuncu Yil University for the treatment of atopic dermatitis in children. The formulation consists of four specific bacterial strains: *Bifidobacterium bifidum*, *Lactobacillus acidophilus*, *Lactobacillus casei*, and *Lactobacillus salivarius*. The supplement is intended to modulate the gut-skin axis and immune response to alleviate symptoms of medium-to-heavy atopic dermatitis. Clinical study results indicated that the probiotic was effective in reducing SCORAD (Scoring Atopic Dermatitis) index levels in pediatric patients, although it did not significantly impact other immunological markers such as serum cytokines (IL-2, IL-4, IL-5, IL-6, IL-10, TNF-α, IFN-γ), eosinophil cationic protein (ECP), or total and specific IgE levels.

Brand names
Probiotic Pur
Other names
probiotic ® purMulti-strain probiotic supplement (Yuzuncu Yil University)

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