Drug intelligence / Profile preview

Probiotical

Development stage
Unknown
Lead developer
Probiotical
Modality
Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Probiotical is a brand name for a range of probiotic products developed and manufactured by the company Probiotical. These products contain live microorganisms, typically specific strains of beneficial bacteria such as Lactobacillus and Bifidobacterium species, designed to confer health benefits when administered in adequate amounts. The primary mechanism of action involves modulation and restoration of the gut microbiota, inhibition of pathogenic microorganisms, production of bioactive metabolites (such as short-chain fatty acids), reinforcement of gut barrier function, vitamin synthesis, bile salt metabolism, enzymatic activity enhancement, toxin neutralization, and immunomodulation. Clinical uses include prevention or treatment of antibiotic-associated diarrhea, acute infectious diarrhea, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), bacterial vaginosis, pediatric candidemia/candiduria, necrotizing enterocolitis in neonates, upper respiratory tract infections (URTIs), blood pressure regulation support in some populations and ventilator-associated pneumonia. Evidence for efficacy varies by strain and indication; proven benefits are strongest for certain types/strains in acute diarrhea and antibiotic-associated diarrhea[1][4][5][6][8].

Brand names
Probiotical

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