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probiotics + glutamine is a combination therapy investigated for its protective effects on the gastrointestinal tract during cancer treatment. Probiotics, which are live microorganisms, work by restoring the balance of the gut microbiome, enhancing the intestinal mucosal barrier, and modulating the local immune response. Glutamine, a non-essential amino acid, serves as a critical energy source for rapidly dividing cells like enterocytes and helps maintain the structural integrity of the intestinal lining. Together, they are used to prevent and treat acute radiation enteritis and radiation-induced diarrhea in patients undergoing pelvic radiotherapy, such as those with locally advanced rectal cancer.
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