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probiotics-The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Development stage: Unknown
Lead developer: Nanjing Drum-Tower Hospital
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

A probiotic powder intervention developed and studied by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School. It is currently being evaluated in a randomized, double-blind clinical trial (NCT03756623) to assess its impact on gut microbiome composition and metabolic markers in healthy individuals. The intervention consists of 0.5g of probiotic powder administered orally three times daily over a 12-week period. The study aims to characterize changes in gut microbiota and their correlation with metabolic parameters such as fasting glucose, insulin levels, and lipid profiles, comparing the effects to those of metformin and a placebo.

Other names: Probiotics powder

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