procaine penicillin + gentamicin + amoxicillin

This refers to a set of antibiotic regimens evaluated in the Simplified Antibiotic Therapy Trial (SATT) conducted by Aga Khan University. The trial compared simplified outpatient antibiotic treatments for neonatal sepsis (possible serious bacterial infection) in infants aged 0-59 days whose families refused hospitalization in resource-limited settings. The regimens involve combinations of procaine penicillin (a long-acting beta-lactam), gentamicin (an aminoglycoside), and amoxicillin (a broad-spectrum penicillin). Specifically, the trial tested a 7-day course of intramuscular (IM) gentamicin plus oral amoxicillin, and a switch therapy consisting of 2 days of IM procaine penicillin and gentamicin followed by 5 days of oral amoxicillin, comparing them to the standard 7-day IM procaine penicillin and gentamicin reference therapy.

Other names

SATT antibiotic regimensSimplified Antibiotic Therapy Trial regimens