ProctoFiz

ProctoFiz is a multi-ingredient herbal topical ointment developed by Sheba Medical Center and Tel Aviv University for the treatment of chronic anal fissure. The formulation is primarily composed of hemp seed oil, which interacts with the endocannabinoid system (ECS) to provide analgesic, anti-inflammatory, and tissue-healing properties. Additional botanical components include calendula, sweet almond, myrtle, arnica, and seaweed extract. Marketed as a medical device in Israel, ProctoFiz has demonstrated significant symptom improvement in clinical studies, showing comparable or superior efficacy to standard nifedipine-lidocaine treatments for anal fissure healing and pain relief.

Brand names

ProctoFiz

Other names

hemp-herbal topical ointment