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ProctoFiz MD is a plant-based topical cream developed by ESPA Biomedical for the management and treatment of chronic anal fissures. Registered as a medical device with the Israeli Ministry of Health, the formulation contains a synergistic blend of natural ingredients, including hemp seed oil, calendula, sweet almond, myrtle, arnica, and seaweed extract. It acts as a local anesthetic, antiseptic, anti-inflammatory, and skin-regenerating agent to alleviate pain, reduce bleeding, and promote wound healing. In Israel, it is marketed in partnership with CTS.
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