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ProFine
- Development stage
- Preclinical
- Lead developer
- MetCure Therapeutics
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
ProFine is a proprietary flavonoid composition being developed by MetCure Therapeutics as a botanical drug for the treatment of prostate cancer. The agent is designed to modulate multiple signaling pathways involved in tumor progression, specifically targeting Heat Shock Protein 90 (HSP90), the Androgen Receptor (AR), and Activating Transcription Factor 3 (ATF3). By influencing these targets, ProFine aims to inhibit the growth and survival of prostate cancer cells. It is currently in the preclinical stage of development and is categorized as both a nutraceutical and a botanical drug candidate.
- Brand names
- ProFine
- Other names
- ProFine
02
Targets
ATF3 (Activating transcription factor 3)Heat shock protein 90/Androgen receptor axisAR (Adrenergic receptors)
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