proflavine hemisulphate

Proflavine hemisulphate is the hemisulfate salt of proflavine, an acridine-derived compound used primarily as a topical antiseptic and disinfectant. It acts as a bacteriostatic agent against many gram-positive bacteria and is applied to superficial wounds, cuts, grazes, insect bites, and burns to prevent infection. Its mechanism of action involves intercalation into DNA base pairs, disrupting DNA synthesis and leading to mutations that inhibit bacterial reproduction. Proflavine also functions as a fluorescent contrast agent in high-resolution optical imaging for visualizing cell nuclei in diagnostic procedures. Due to its toxicity and carcinogenicity in mammals, its use is restricted mainly to topical applications[1][2][5][7].

Brand names

Proflavine Hemisulphate LotionTriple DyeKerr Triple Dye

Other names

proflavin hemisulfateproflavin sulfateproflavine sulfatediaminoacridine hemisulfate