Drug intelligence / Profile preview

profoxydim

Development stage
Unknown
Lead developer
BASF
Modality
Small Molecules
01

Overview

Profoxydim is a post-emergence herbicide belonging to the cyclohexenone (cyclic ketone) class, primarily used for the control of annual and perennial grassy weeds in crops such as rice, soybeans, and tobacco[1][7]. Its mechanism of action involves inhibition of acetyl-CoA carboxylase (ACCase), an enzyme essential for fatty acid biosynthesis in plants. By blocking this enzyme, profoxydim disrupts cell membrane formation and other vital cellular processes in susceptible grasses[10]. It is not intended or approved for pharmaceutical use in humans or animals. Profoxydim has been associated with certain hazards including skin sensitization, suspected carcinogenicity, and reproductive toxicity[2].

Other names
N-[2-(4-chlorophenoxy)propoxy]butanimidoyl]-3-hydroxy-5-(thian-3-yl)cyclohex-2-en-1-oneCAS 139001-49-3CAS139001-49-3CAS-139001-49-3T7QYT6EW74T-7QYT6EW74T 7QYT6EW74DB14820DB-14820DB 14820
02

Targets

Plant acetyl-CoA carboxylase, carboxyltransferase domain

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