Progepril

Progepril is a multi-ingredient botanical dietary supplement formulated to manage menstrual cycle irregularities and symptoms of premenstrual syndrome (PMS). It contains extracts of *Dioscorea villosa* (Wild Yam), *Vitex agnus-castus* (Chasteberry), and *Turnera diffusa* (Damiana). The supplement is particularly utilized in women for whom synthetic hormonal treatments are contraindicated, such as breast cancer survivors or individuals with high genetic risk for breast cancer. Its mechanism involves the phyto-progestogenic properties of its components; specifically, *Vitex agnus-castus* contains dopaminergic compounds that bind to pituitary dopamine D2 receptors, leading to a reduction in prolactin secretion and stabilization of the luteal phase. *Dioscorea villosa* provides diosgenin, a plant steroid often associated with progesterone-like effects. Together, these ingredients work to regularize menstrual flow and duration while alleviating psychophysical symptoms associated with the menstrual cycle.

Brand names

Progepril

Other names

Progepril