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Project 2
- Development stage
- Preclinical
- Lead developer
- Chongqing Pharmaceutical
- Modality
- Small Molecules
01
Overview
Project 2 is a preclinical-stage small molecule inhibitor of **Bruton's tyrosine kinase (BTK)** being developed by **Chongqing Pharmaceutical** (specifically through the Chongqing Pharmaceutical Research Institute). Positioned as a "me-better" candidate in the company's pipeline, it is designed to treat **B-cell related lymphomas**. BTK is a critical non-receptor tyrosine kinase in the B-cell receptor (BCR) signaling pathway, which is essential for the survival, proliferation, and differentiation of B-lymphocytes. In many B-cell malignancies, this pathway is constitutively active, driving tumor growth. By selectively inhibiting BTK, Project 2 aims to block these oncogenic signals, potentially offering improved efficacy or safety compared to existing therapies for patients with B-cell lymphomas.
- Other names
- BTK inhibitor (Chongqing Pharmaceutical)Chongqing Pharmaceutical-BTK-small molecule-B-cell related lymphoma
02
Targets
BTK (Bruton tyrosine kinase)
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