Drug intelligence / Profile preview

Prolox-F Solution

Development stage
Unknown
Lead developer
Percos India
Modality
Small Molecules
Administration
Topical
01

Overview

Prolox-F Solution is a topical combination therapy developed by Percos India Pvt Ltd for the treatment of androgenetic alopecia (male pattern hair loss). It contains two active pharmaceutical ingredients: minoxidil (5% w/v) and finasteride (0.1% w/v). Minoxidil acts as a vasodilator and potassium channel opener that improves blood flow, oxygen, and nutrient delivery to hair follicles, thereby stimulating hair growth. Finasteride serves as a 5-alpha-reductase inhibitor that reduces levels of dihydrotestosterone (DHT), the hormone primarily responsible for hair follicle miniaturization in androgenetic alopecia. This dual-action approach aims to prevent further hair thinning and promote regrowth when applied topically to the scalp.

Brand names
Prolox-F SolutionProlox-F
Other names
Finasteride 0.1% + Minoxidil 5% topical solution
02

Targets

KATP channel (ATP-sensitive potassium channel)SRD5A2 (Steroid 5-alpha-reductase type II)

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