Drug intelligence / Profile preview

PROMY

Development stage
Unknown
Lead developer
Citi Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

PROMY is a branded generic formulation of omeprazole, a proton pump inhibitor (PPI) developed and marketed by Citi Pharma. It is a substituted benzimidazole that acts as a small molecule inhibitor of the gastric H+/K+ ATPase enzyme system (the proton pump) located on the secretory surface of the gastric parietal cell. By binding covalently to cysteine residues via disulfide bridges on the alpha subunit of the pump, it irreversibly inhibits the final step of gastric acid secretion. PROMY is administered orally and is available as a 20 mg capsule or a film-coated MUPS (Multiple-Unit Pellet System) tablet containing enteric-coated micro pellets. It is indicated for the treatment of acid-related disorders including gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome.

Brand names
PROMY
Other names
Omeprazole 20 mgOmeprazole20 mgOmeprazole-20 mg
02

Targets

ATP4A (Potassium–transporting ATPase alpha chain 1)

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