Drug intelligence / Profile preview

Prontosan Wound Gel

Development stage
Unknown
Lead developer
B. Braun
Modality
Small Molecules
Administration
Topical
01

Overview

Prontosan Wound Gel is a topical wound care gel developed and manufactured by B. Braun for management of acute and chronic wounds and burns. It is a combination formulation containing polihexanide, also known as polyhexamethylene biguanide, together with betaine surfactant; the product is used to cleanse, moisturize, and decontaminate the wound bed between dressing changes while helping disrupt and prevent biofilm formation. Rather than acting through a conventional single molecular target, its therapeutic effect derives from broad topical antimicrobial activity of polihexanide and surface-cleansing surfactant action of betaine, supporting a moist wound-healing environment in indications such as traumatic wounds, venous ulcers, arterial ulcers, diabetic ulcers, and pressure ulcers.

Brand names
Prontosan Wound Gel
Other names
polihexanide + betaine wound gelpolyhexamethylene biguanide + betaine wound gelPHMB + betaine wound gel
02

Targets

PGN (Peptidoglycan)

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