Drug intelligence / Profile preview

PRONULIFE RenaProtect

Development stage
Unknown
Lead developer
Glac Biotech
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

PRONULIFE RenaProtect is a clinically-proven probiotic blend developed by GLAC Biotech Co., Ltd. for kidney health and renal support. The formulation consists of three specific human-derived probiotic strains: *Lactobacillus acidophilus* TYCA06, *Bifidobacterium longum* subsp. *infantis* BLI-02, and *Bifidobacterium bifidum* VDD088. It is designed to modulate the gut-kidney axis, a mechanism that helps reduce the accumulation of uremic toxins and systemic pro-inflammatory cytokines such as Interleukin-6 (IL-6), Interleukin-18 (IL-18), and Tumor Necrosis Factor-alpha (TNF-α). Clinical studies in patients with chronic kidney disease (CKD) have demonstrated that the product can slow the decline of the estimated glomerular filtration rate (eGFR) and improve the composition of the gut microbiota. It is marketed as a functional food ingredient or dietary supplement and is available in oral dosage forms including capsules, tablets, and powdered sachets.

Brand names
PRONULIFE RenaProtect
Other names
RenaProtect
02

Targets

IL18 (Interleukin-18)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))

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