Drug intelligence / Profile preview

propiverine

Development stage
Phase 4
Lead developer
APOGEPHA Arzneimittel
Modality
Small Molecules
Administration
Oral
01

Overview

Propiverine is a small molecule antimuscarinic and calcium channel antagonist used primarily to treat symptoms of overactive bladder (OAB), including urinary urgency, frequency, and incontinence. It acts as a detrusor muscle relaxant by blocking muscarinic receptors in the bladder and modulating calcium influx into smooth muscle cells. This dual mechanism reduces involuntary contractions of the bladder muscle and increases bladder capacity. Propiverine is available as tablets and prolonged-release capsules for oral administration[2][3][5][6][8]. The drug was originally developed by Apogepha.

Brand names
DetrunormDetrunorm XLMictonetMictonettenMictonormMictonorm UnoMictonorm XLMictorylMictoryl PediatricProprinorm
Other names
propiverine hydrochloridePropiverina (Spanish, Italian)Propiverinum (Latin)1-methylpiperidin-4-yl 2,2-diphenyl‑2‑propoxyacetate
02

Targets

ADRA1A (α1A)CHRM3 (M3)CaV1.2 (Voltage-dependent L-type calcium channel subunit alpha-1C)

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