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propofol + lidocaine + fentanyl

Development stage: Unknown
Lead developer: AkzoNobel
Modality: Small Molecules
Administration: Intravenous

Overview

A combination of three medications used for procedural sedation and analgesia. This combination leverages propofol's sedative properties, lidocaine's ability to reduce injection pain, and fentanyl's analgesic effects. The synergistic interaction allows for lower doses of each component, potentially reducing side effects while maintaining efficacy. Commonly used in endoscopic procedures, cataract surgeries, and other invasive medical interventions requiring moderate to deep sedation.

Other names: lidocaine + propfol + fentanyl-Tanta University-lumbar spinal stenosis-spinal cord tumorTIVA with lidocaine, propofol, and fentanyl

Targets

GABRR (GABA-A receptor subunit rho)NaV (Voltage-gated sodium channels)MOR (Mu opioid receptor)

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