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Propofol WZF
- Development stage
- Unknown
- Lead developer
- AkzoNobel
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Propofol WZF is an intravenous, short-acting anesthetic agent containing propofol, a substituted phenol derivative used for the induction and maintenance of general anesthesia. It primarily acts as a positive allosteric modulator of the gamma-aminobutyric acid type A (GABA-A) receptor, enhancing inhibitory neurotransmission in the central nervous system. In the context of clinical research conducted by the Silesian University of Medicine, Propofol WZF was utilized for anesthesia induction in patients undergoing open renal surgery to evaluate the efficacy of thoracic paravertebral blocks in managing postoperative pain and reducing subsequent opioid requirements.
- Brand names
- Propofol WZF
- Other names
- propofol2,6-diisopropylphenol
02
Targets
GABRR (GABA-A receptor subunit rho)NaV (Voltage-gated sodium channels)Kinesin (Kinesin motor family)
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