propolis special extract GH 2002

Propolis cream, specifically the formulation containing 0.5% propolis special extract GH 2002 (marketed as Herpetino®), is a topical phytotherapeutic agent used for the treatment of herpes labialis (cold sores). Developed by Harras Pharma Curarina GmbH, this botanical extract exerts antiviral effects against both herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). In addition to its antiviral properties, the extract provides antibacterial, anti-inflammatory, and local anesthetic benefits, which collectively facilitate the healing process. Clinical evidence from Phase 3 randomized trials has demonstrated that propolis cream is superior to aciclovir 5% cream, achieving faster lesion encrustation and epithelization, typically within a median of 3 days compared to 4 days for aciclovir.

Brand names

Herpetino

Other names

propolis creampropolis 0.5% cream