Propoxycaine

Propoxycaine is a local anesthetic of the ester type, chemically classified as a para-aminobenzoic acid ester. It functions by reversibly binding to and blocking voltage-gated sodium channels in nerve cells, which inhibits the ionic flux essential for the conduction of nerve impulses. This action leads to a temporary loss of sensation and localized pain relief. Historically, Propoxycaine was primarily utilized in dental procedures and minor surgeries, often in combination with procaine to achieve a more rapid onset and longer duration of anesthetic effect. Although its mechanism of action is well-established, its usage has declined with the advent of newer anesthetics, and it was removed from the US market in 1996.

Brand names

RavocaineBlockainPravocaineRanocaine

Other names

Propoxycaine hydrochloride2-(diethylamino)ethyl 4-amino-2-propoxybenzoate hydrochloride4-Amino-2-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochlorideBenzoic acid, 4-amino-2-propoxy-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)Benzoic acid, 4-amino-2-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloridePropoxycaine HClRovocaine hydrochlorideUnii-K490D39G46Unii-K-490D39G46Unii-K 490D39G46