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propylene glycol + polyethylene glycol
- Development stage
- Phase 4
- Lead developer
- Alcon
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
Propylene glycol + polyethylene glycol is a combination topical lubricant (artificial tear) formulation used for the treatment of dry eye disease. It acts as a demulcent by increasing the volume of the tear film and forming a protective gel matrix on the ocular surface. This matrix helps reduce tear evaporation and drainage, maintaining moisture and protecting the corneal epithelium. A specific preservative-free formulation, Glicolub Ultra (0.3% propylene glycol and 0.4% polyethylene glycol 400), developed by Tecnoquimicas, is used to manage mild to moderate dry eye symptoms. The combination is also widely known under the brand name Systane, developed by Alcon.
- Brand names
- Glicolub UltraSystane
- Other names
- propylene glycol + polyethylene glycol 400
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